Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834728 | 0.91 | — | — | |
| SCHEMBL690353 | 0.91 | — | — | |
| SCHEMBL690239 | 0.91 | — | — | |
| Crotonic Acid SCHEMBL38664646 | 0.90 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2ALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL31275468 | 0.89 | — | — | |
| Methyl Alcohol SCHEMBL10525144 | 0.89 | HCAR2 (0.57) | HCAR2KEAP1NFE2L2ALDH1A1ALOX15 | |
| Benzene SCHEMBL27601984 | 0.87 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2ALDH1A1ALOX15 | |
| SCHEMBL31172069 | 0.86 | HCAR2 (0.65) | HCAR2KEAP1NFE2L2ALDH1A1ALOX15 | |
| (2E)-Hexenoic Acid SCHEMBL2191923 | 0.85 | HCAR2 (0.58) | HCAR2KEAP1NFE2L2ALDH1A1ALOX15 | |
| (2E)-Hexenoic Acid SCHEMBL28035225 | 0.85 | HCAR2 (0.58) | HCAR2KEAP1NFE2L2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111650286-A | Method for detecting medium-long chain fatty acid in human serum based on gas chromatography-mass spectrometry | 上海中科新生命生物科技有限公司 | 2020-09-11 | — | — | CN | claimed |
| CN-112433012-A | Construction method and application of chicken quality fatty acid evaluation model | 华南农业大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-111650286-A | Method for detecting medium-long chain fatty acid in human serum based on gas chromatography-mass spectrometry | 上海中科新生命生物科技有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-8791158-B2 | Methods of treating meibomian gland dysfunction | GTX, INC. (US) | 2014-07-29 | — | — | US | disclosed |
| EP-2523556-A1 | METHODS OF TREATING MEIBOMIAN GLAND DYSFUNCTION | Gtx, Inc. (US) | 2012-11-21 | — | — | EP | disclosed |
| US-20110172302-A1 | METHODS OF TREATING MEIBOMIAN GLAND DYSFUNCTION | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-07-14 | — | — | US | disclosed |
| WO-2011085385-A1 | METHODS OF TREATING MEIBOMIAN GLAND DYSFUNCTION | GTX, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| CN-101265185-B | Process for preparing and separating methyl docosapentaenoate and methyl docosahexenoate | UNIV TIANJIN | 2010-07-21 | — | — | CN | disclosed |
| CN-101265185-A | Process for preparing and separating methyl docosapentaenoate and methyl docosahexenoate | UNIV TIANJIN (CN) | 2008-09-17 | — | — | CN | disclosed |
| JP-2004002269-A | CARCINOGENESIS-PREVENTING AGENT | UNIV NIHON | 2004-01-08 | — | — | JP | disclosed |
| US-6242013-B1 | Method and composition for enhancing oleic acid content of milk produced by ruminants | LAND O'LAKES, INC. | 2001-06-05 | — | — | US | disclosed |
| EP-0913473-A1 | PROCESS FOR PRODUCING ICOSAPENTAENOIC ACID BY GENETIC RECOMBINATION | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5798259-A | Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172302-A1 | METHODS OF TREATING MEIBOMIAN GLAND DYSFUNCTION | MGLL, LIPA, PON1 | HCAR2 2390/4885KEAP1 1020/4885NFE2L2 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.