Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dl-Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | CTSC | P53634 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL1094608 | 1.00 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL3062589 | 1.00 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL21899689 | 1.00 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL8010875 | 0.96 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL1828216 | 0.96 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL4612406 | 0.95 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL27702676 | 0.95 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL4614788 | 0.95 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL22468204 | 0.95 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL2478801 | 0.95 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861266-A | Biosynthesis method of bacillus alkaline protease inhibitory peptide | 天津科技大学 | 2021-12-31 | — | — | CN | claimed |
| CN-116162562-A | Lactobacillus delbrueckii subspecies and culture method and application thereof | 深圳市盐田区人民医院 | 2023-05-26 | — | — | CN | disclosed |
| CN-116083269-A | Lactobacillus delbrueckii subspecies indicum and culture method and application thereof | 深圳市盐田区人民医院 | 2023-05-09 | — | — | CN | disclosed |
| US-11554116-B2 | Agent for preventing and/or treating alzheimer's disease | KYOTO UNIVERSITY (JP) | 2023-01-17 | — | — | US | disclosed |
| CN-113861266-A | Biosynthesis method of bacillus alkaline protease inhibitory peptide | 天津科技大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-113861266-A | Biosynthesis method of bacillus alkaline protease inhibitory peptide | 天津科技大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-107312068-B | Fluorescent probe for detecting activity of proline isomerase, preparation and application thereof | 浙江大学 | 2021-02-09 | — | — | CN | disclosed |
| EP-3646872-A1 | AGENT FOR PREVENTING AND/OR TREATING ALZHEIMER'S DISEASE | Kyoto University (JP) | 2020-05-06 | — | — | EP | disclosed |
| CN-110944639-A | Agent for preventing and/or treating alzheimer's disease | 国立大学法人京都大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-105505817-B | A kind of lactobacillus plantarum and its application in fermentation pickle cured meat product | 中国肉类食品综合研究中心 | 2019-01-15 | — | — | CN | disclosed |
| CN-107312068-A | A kind of fluorescence probe for detecting proline isomerase activity and preparation and application | 浙江大学 | 2017-11-03 | — | — | CN | disclosed |
| CN-104560802-A | Fermentation strain and fermentation agent for canned meat products | CHINA MEAT RES CT | 2015-04-29 | — | — | CN | disclosed |
| CN-104560808-A | Lactobacillus plantarum strain and fermentation method of canned meat products | CHINA MEAT RES CT | 2015-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11554116-B2 | Agent for preventing and/or treating alzheimer's disease | PSEN1, APP, PSEN2 | SLC7A5 1925/4885ALPI 553/4885PKM 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.