Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21900250 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL28638670 | 0.84 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL19873909 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL19873974 | 0.78 | PTGDR2 (0.34) | ALDH1A1KDM4EPOLBMAPTPTGDR2 | |
| SCHEMBL19873785 | 0.77 | POLB (0.39) | ALDH1A1KDM4EPOLBMAPTPTGDR2 | |
| SCHEMBL21900234 | 0.76 | MAPT (0.32) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL19873819 | 0.76 | PTGDR2 (0.38) | ALDH1A1POLBPTGDR2 | |
| SCHEMBL19873755 | 0.76 | PTGDR2 (0.36) | ALDH1A1PTGDR2 | |
| SCHEMBL30178454 | 0.74 | ALDH1A1 (0.34) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL21900222 | 0.72 | ALDH1A1 (0.36) | ALDH1A1KDM4EPOLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |
| EP-3708566-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2020-09-16 | — | — | EP | disclosed |
| EP-3237403-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2020-05-06 | — | — | EP | disclosed |