Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 8/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19873785 | 0.91 | POLB (0.39) | PTGDR2AKR1A1AKR1B1ALDH1A1SLC6A2 | |
| SCHEMBL19874003 | 0.81 | GNRHR (0.40) | AKR1B1ALDH1A1 | |
| SCHEMBL19873755 | 0.79 | PTGDR2 (0.36) | PTGDR2AKR1A1AKR1B1ALDH1A1PDE10A | |
| SCHEMBL19873974 | 0.77 | PTGDR2 (0.34) | PTGDR2AKR1A1AKR1B1ALDH1A1POLB | |
| SCHEMBL21900250 | 0.76 | ALDH1A1 (0.38) | ALDH1A1POLB | |
| SCHEMBL21900233 | 0.76 | ALDH1A1 (0.40) | PTGDR2ALDH1A1POLB | |
| SCHEMBL19873740 | 0.75 | GNRHR (0.38) | PTGDR2ALDH1A1SLC6A2POLB | |
| SCHEMBL30178406 | 0.74 | GNRHR (0.41) | PTGDR2 | |
| SCHEMBL19873720 | 0.74 | GNRHR (0.41) | PTGDR2 | |
| SCHEMBL19873801 | 0.70 | GNRHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |
| US-10246422-B2 | Heterocyclic compounds and use thereof in medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-04-02 | — | — | US | disclosed |
| US-20180050992-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2018-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180050992-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS | MC1R, CALCRL, BDKRB2 | PTGDR2 112/4885AKR1A1 515/4885AKR1B1 488/4885 |
| US-10246422-B2 | Heterocyclic compounds and use thereof in medicine and in cosmetics | MC1R, BDKRB2, CCKBR | PTGDR2 127/4885AKR1A1 454/4885AKR1B1 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.