Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26652832 | 0.80 | GRIN2B (0.33) | NOTUM | |
| SCHEMBL30176373 | 0.78 | KDM4E (0.33) | NOTUM | |
| SCHEMBL23886767 | 0.78 | KDM4E (0.33) | NOTUM | |
| SCHEMBL26652636 | 0.75 | NR3C1 (0.33) | — | |
| SCHEMBL23883773 | 0.75 | NR3C1 (0.36) | — | |
| SCHEMBL30234871 | 0.75 | NR3C1 (0.36) | — | |
| SCHEMBL23886957 | 0.74 | PIK3CA (0.34) | — | |
| SCHEMBL30176372 | 0.74 | PIK3CA (0.34) | — | |
| SCHEMBL29536350 | 0.71 | TGFBR1 (0.42) | — | |
| SCHEMBL21856715 | 0.71 | TGFBR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081257-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-04-23 | — | — | WO | disclosed |