Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5949564 | 1.00 | ESR1 (0.46) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL25976541 | 1.00 | ESR1 (0.46) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL278974 | 0.98 | CYP19A1 (0.46) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL14174015 | 0.97 | ESR1 (0.46) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL10049949 | 0.94 | ESR1 (0.47) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL2605488 | 0.93 | PTGS2 (0.52) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL12618570 | 0.93 | ESR1 (0.54) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL13055135 | 0.92 | PTGS2 (0.51) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL14174017 | 0.89 | ESR1 (0.43) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 | |
| SCHEMBL863225 | 0.88 | PTGS2 (0.40) | ESR1CYP19A1CYP11B2PTGS2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10935898-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2021-03-02 | — | — | US | disclosed |
| US-20200124996-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2020-04-23 | — | — | US | disclosed |