SCHEMBL863225

SCHEMBL863225

Cc1ccc(/C(=C/c2ccc(N(c3ccc(CO)cc3)c3ccc(CO)cc3)cc2)c2ccccc2)cc1C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.40
S1PR1 P21453 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CYP2D6 P10635 1/20 0.38
ESR1 P03372 2/20 0.37
CYP19A1 P11511 1/20 0.36
CYP11B2 P19099 1/20 0.36
LMNA P02545 1/20 0.36
ESR2 Q92731 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20464178 0.90 S1PR1 (0.38) PTGS2S1PR1CES2CES1CYP2D6
SCHEMBL13030248 0.90 PTGS2 (0.45) PTGS2CES2CES1CYP2D6ESR1
SCHEMBL13050003 0.89 PTGS2 (0.44) PTGS2CES2CES1CYP2D6ESR1
SCHEMBL5949564 0.88 ESR1 (0.46) PTGS2CYP2D6ESR1CYP19A1CYP11B2
SCHEMBL21900941 0.88 ESR1 (0.46) PTGS2CYP2D6ESR1CYP19A1CYP11B2
SCHEMBL25976541 0.88 ESR1 (0.46) PTGS2CYP2D6ESR1CYP19A1CYP11B2
SCHEMBL12189993 0.87 PTGS2 (0.52) PTGS2CES2CES1CYP2D6ESR1
SCHEMBL19911156 0.87 PTGS2 (0.52) PTGS2CES2CES1CYP2D6ESR1
SCHEMBL2605488 0.87 PTGS2 (0.52) PTGS2CYP2D6ESR1CYP19A1CYP11B2
SCHEMBL13741445 0.87 PTGS2 (0.52) PTGS2CES2CES1CYP2D6ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120073661-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-03-29 US disclosed