Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305897 | 0.83 | ELANE (0.52) | MEN1KMT2ASMN1; SMN2L3MBTL1ELANE | |
| SCHEMBL18792766 | 0.82 | ELANE (0.46) | MEN1KMT2ASMN1; SMN2L3MBTL1ROCK2 | |
| SCHEMBL22990404 | 0.82 | ALDH1A1 (0.55) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL23420957 | 0.81 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1ROCK2 | |
| SCHEMBL12157064 | 0.81 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1ROCK2 | |
| SCHEMBL24541057 | 0.81 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1ROCK2 | |
| SCHEMBL24240506 | 0.80 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2L3MBTL1ROCK2 | |
| SCHEMBL19502636 | 0.79 | ROCK2 (0.41) | MEN1KMT2ASMN1; SMN2L3MBTL1ROCK2 | |
| SCHEMBL21120303 | 0.79 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1ROCK2 | |
| SCHEMBL19503127 | 0.79 | MAPT (0.41) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081744-A1 | IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE | TOLLNINE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |