Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18119800 | 0.84 | POLB (0.46) | HPGDHDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL24263874 | 0.79 | HPGD (0.52) | HPGDHDAC4HDAC6 | |
| SCHEMBL17637139 | 0.78 | MEN1 (0.52) | HPGDHDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL18119788 | 0.78 | KMT2A (0.56) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL25457352 | 0.77 | HTT (0.58) | ALDH1A1LTB4R2TPSAB1 | |
| SCHEMBL31742277 | 0.77 | HDAC3 (0.46) | HPGDHDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL21786938 | 0.77 | MEN1 (0.49) | HPGDHDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL17721289 | 0.77 | HTT (0.43) | HPGDHDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL18121970 | 0.76 | SMN1; SMN2 (0.42) | HPGDALDH1A1SMN1; SMN2TPSAB1EPHX2 | |
| SCHEMBL18270260 | 0.76 | SMN1; SMN2 (0.40) | HPGDHDAC1HDAC6SMN1; SMN2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081744-A1 | IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE | TOLLNINE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |