Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18119788 | 0.84 | KMT2A (0.56) | POLBSMN1; SMN2HDAC1KMT2AKDM4E | |
| SCHEMBL25457352 | 0.84 | HTT (0.58) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL21901451 | 0.84 | HPGD (0.48) | SMN1; SMN2HDAC1ALDH1A1HDAC2HDAC3 | |
| SCHEMBL18121970 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL17637139 | 0.82 | MEN1 (0.52) | SMN1; SMN2HDAC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL21786938 | 0.81 | MEN1 (0.49) | HDAC1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL21151955 | 0.81 | ERCC1 (0.50) | POLBHDAC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL29864889 | 0.81 | HTT (0.45) | SMN1; SMN2HDAC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17721289 | 0.81 | HTT (0.43) | SMN1; SMN2HDAC1ALDH1A1LMNAHTT | |
| SCHEMBL18270260 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2HDAC1KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024013355-A1 | HYDROGELS FOR CELL THERAPY | ADOCIA (FR) | 2024-01-18 | — | — | WO | disclosed |
| US-20230277678-A1 | COMPOUNDS CAPABLE OF BINDING TO PROTEINS AND CONJUGATES OBTAINED FROM THESE COMPOUNDS | MC SAF (FR) | 2023-09-07 | — | — | US | disclosed |
| US-20180135121-A1 | PORE-FORMING PROTEIN CONJUGATE COMPOSITIONS AND METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-05-17 | — | — | US | disclosed |
| US-20160287734-A1 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230277678-A1 | COMPOUNDS CAPABLE OF BINDING TO PROTEINS AND CONJUGATES OBTAINED FROM THESE COMPOUNDS | SHBG, SERPINA6, F13B | POLB 3960/4885SMN1; SMN2 2078/4885HDAC1 1815/4885 |
| US-20160287734-A1 | 18F LABELING OF PROTEINS USING SORTASES | SORT1, ANPEP, SPG11 | POLB 4242/4885SMN1; SMN2 4600/4885HDAC1 3420/4885 |
| US-20180135121-A1 | PORE-FORMING PROTEIN CONJUGATE COMPOSITIONS AND METHODS | TIAL1, NUP93, PORCN | POLB 61/4885SMN1; SMN2 4763/4885HDAC1 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.