Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22415053 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL25939697 | 0.83 | HPGD (0.44) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL18119800 | 0.83 | POLB (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL18119788 | 0.80 | KMT2A (0.56) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL25457352 | 0.80 | HTT (0.58) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL18270260 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1HPGDTPSAB1 | |
| SCHEMBL31041169 | 0.78 | TPSAB1 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL31041170 | 0.78 | TPSAB1 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL29780633 | 0.78 | TPSAB1 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL17056078 | 0.78 | TPSAB1 (0.40) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160287734-A1 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287734-A1 | 18F LABELING OF PROTEINS USING SORTASES | SORT1, ANPEP, SPG11 | SMN1; SMN2 4600/4885KMT2A 4765/4885MEN1 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.