Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 3/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291406 | 1.00 | LMNA (0.58) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL25934670 | 1.00 | LMNA (0.58) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL27291420 | 1.00 | LMNA (0.58) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL27291402 | 0.95 | LMNA (0.50) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL18644645 | 0.95 | LMNA (0.50) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL32670368 | 0.93 | L3MBTL1 (0.50) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL32670311 | 0.91 | LMNA (0.48) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL14199854 | 0.91 | LMNA (0.48) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL26073710 | 0.88 | LMNA (0.50) | LMNAL3MBTL1TDP1TOP1KDM4E | |
| SCHEMBL13026578 | 0.88 | LMNA (0.50) | LMNAL3MBTL1TDP1TOP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146896-A1 | BICYCLIC-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146892-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2020081744-A1 | IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE | TOLLNINE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |