Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | BID | P55957 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | IAPP | P10997 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014244 | 0.94 | LIPG (0.46) | LIPGALOX5PTGS2TYRBID | |
| SCHEMBL10982682 | 0.85 | LIPG (0.45) | LIPGALOX5PTGS2TYRBID | |
| SCHEMBL8517572 | 0.84 | LIPG (0.39) | LIPGALOX5PTGS2TYRBID | |
| SCHEMBL3675447 | 0.82 | TAAR1 (0.39) | — | |
| SCHEMBL1970435 | 0.82 | LIPG (0.40) | LIPGALOX5PTGS2TYRBID | |
| SCHEMBL942781 | 0.81 | LIPG (0.47) | LIPGALOX5PTGS2TYRCYP3A4 | |
| Water SCHEMBL28038476 | 0.79 | LIPG (0.46) | LIPGALOX5PTGS2TYRCYP3A4 | |
| SCHEMBL27882264 | 0.79 | LIPG (0.46) | LIPGALOX5PTGS2TYRCYP3A4 | |
| SCHEMBL28003211 | 0.79 | LIPG (0.46) | LIPGALOX5PTGS2TYRCYP3A4 | |
| SCHEMBL630180 | 0.79 | LIPG (0.41) | LIPGALOX5PTGS2TYRBID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081852-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-04-23 | — | — | WO | disclosed |
| CN-108368126-A | Process for preparing 1, 3-benzodioxole heterocycles | 利奥制药有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-108350274-A | CURABLE ORGANOPOLYSILOXANE COMPOSITION AND CURED PRODUCT THEREOF | 道康宁东丽株式会社 | 2018-07-31 | — | — | CN | disclosed |
| CN-103804723-B | Tyre element and preparation method thereof | 东洋橡胶工业株式会社 | 2016-09-07 | — | — | CN | disclosed |
| CN-104011084-B | The manufacture method of metha crylic polymer | MITSUBISHI RAYON CO.,LTD. (JP) | 2016-03-02 | — | — | CN | disclosed |
| CN-102844335-B | Manufacturing device and manufacturing method of methacryl series polymer | MITSUBISHI RAYON CO | 2015-04-08 | — | — | CN | disclosed |
| CN-104277230-A | METHOD FOR PRODUCING RUBBER MASTER BATCH | TOYO TIRE & RUBBER CO | 2015-01-14 | — | — | CN | disclosed |
| CN-104011084-A | METHOD FOR MANUFACTURING METHACRYLIC POLYMER | MITSUBISHI RAYON CO | 2014-08-27 | — | — | CN | disclosed |
| CN-103804723-A | Tire member and method for manufacturing the same | TOYO TIRE & RUBBER CO | 2014-05-21 | — | — | CN | disclosed |
| CN-102844335-A | Manufacturing device and manufacturing method of methacryl series polymer | MITSUBISHI RAYON CO | 2012-12-26 | — | — | CN | disclosed |
| CN-1087352-A | Process for the preparation of glutarimide copolymers and useful intermediate compounds | ATOCHEM ELF SA (FR) | 1994-06-01 | — | — | CN | disclosed |