SCHEMBL1970435

SCHEMBL1970435

CCCCc1cccc(S)c1S

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.40
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
BID P55957 3/20 0.38
MCL1 Q07820 3/20 0.38
BCL2L1 Q07817 2/20 0.38
BAK1 Q16611 2/20 0.38
KAT8 Q9H7Z6 2/20 0.38
PPARA Q07869 2/20 0.38
IAPP P10997 1/20 0.38
PPARG P37231 1/20 0.38
EP300 Q09472 1/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT5 Q92993 1/20 0.38
SAE1 Q9UBE0 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
TYR P14679 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1967734 0.94 LIPG (0.47) LIPGALOX5PTGS2BIDMCL1
SCHEMBL1965347 0.92 LIPG (0.50) LIPGALOX5PTGS2BIDMCL1
SCHEMBL1971685 0.92 LIPG (0.50) LIPGALOX5PTGS2BIDMCL1
SCHEMBL1968955 0.92 LIPG (0.50) LIPGALOX5PTGS2BIDMCL1
SCHEMBL1971170 0.92 LIPG (0.50) LIPGALOX5PTGS2BIDMCL1
SCHEMBL1969914 0.92 LIPG (0.50) LIPGALOX5PTGS2BIDMCL1
SCHEMBL1972400 0.87 DAO (0.35) LIPGALOX5PTGS2PPARAIAPP
SCHEMBL942781 0.83 LIPG (0.47) LIPGALOX5PTGS2CYP3A4CYP2D6
SCHEMBL13835029 0.82 GABRA1 (0.31)
SCHEMBL8517572 0.82 LIPG (0.39) LIPGALOX5PTGS2BIDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110308502-A The method for preparing molding optical articles PPG工业俄亥俄公司 2019-10-08 CN disclosed
CN-108690180-A Composition and optical goods containing polyurethane-urea and preparation method thereof PPG工业俄亥俄公司 2018-10-23 CN disclosed
CN-108292060-A Colored filter, its manufacturing method and the display equipment including it 三星SDI株式会社 2018-07-17 CN disclosed
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
CN-103443659-A Method for preparing molded optical articles PPG IND OHIO INC 2013-12-11 CN disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
EP-2334661-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS Ube Industries, Ltd. (JP) 2011-06-22 EP disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds PFAS, PUF60, FES LIPG 4754/4885ALOX5 3945/4885PTGS2 4872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.