SCHEMBL21901972

SCHEMBL21901972

O=C1c2ccccc2C(=O)N1C/C=C/F

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 2/20 0.53
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
GLS O94925 1/20 0.46
ALDH1A1 P00352 2/20 0.43
ALDH3A1 P30838 1/20 0.42
RCE1 Q9Y256 1/20 0.42
RPS6KA2 Q15349 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8950475 0.92 CASP3 (0.60) CASP3CA12CA9GLSALDH1A1
SCHEMBL4468251 0.92 CASP3 (0.60) CASP3CA12CA9GLSALDH1A1
SCHEMBL4476083 0.92 CASP3 (0.60) CASP3CA12CA9GLSALDH1A1
SCHEMBL2319856 0.82 CASP3 (0.51) CASP3CA12CA9GLSALDH1A1
SCHEMBL9761279 0.82 CASP3 (0.51) CASP3CA12CA9GLSALDH1A1
SCHEMBL23077378 0.82 CASP3 (0.51) CASP3CA12CA9GLSALDH1A1
SCHEMBL9761288 0.82 CASP3 (0.51) CASP3CA12CA9GLSALDH1A1
SCHEMBL644937 0.82 CASP3 (0.51) CASP3CA12CA9GLSALDH1A1
SCHEMBL25302148 0.82 CASP3 (0.51) CASP3CA12CA9GLSALDH1A1
SCHEMBL12439955 0.82 CASP3 (0.51) CASP3CA12CA9GLSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020079370-A1 HYDROCARBON COPOLYMERS WITH ALTERNATING BLOCKS AND ALKOXYSILANE END GROUPS BOSTIK SA (FR) 2020-04-23 WO disclosed