Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062769 | 0.94 | OPRK1 (0.33) | OPRK1ITGB3ITGA2B | |
| SCHEMBL24239548 | 0.94 | OPRK1 (0.33) | OPRK1ITGB3ITGA2B | |
| SCHEMBL24220950 | 0.89 | NMT2 (0.32) | ITGB3ITGA2B | |
| SCHEMBL18929779 | 0.87 | OPRK1 (0.30) | OPRK1 | |
| SCHEMBL11956479 | 0.84 | KDM4E (0.35) | ITGB3ITGA2B | |
| SCHEMBL21891783 | 0.84 | — | — | |
| SCHEMBL16248631 | 0.84 | KDM4E (0.35) | ITGB3ITGA2B | |
| SCHEMBL17662433 | 0.84 | KDM4E (0.35) | ITGB3ITGA2B | |
| SCHEMBL20016488 | 0.83 | OPRK1 (0.33) | OPRK1ITGB3ITGA2B | |
| SCHEMBL23191800 | 0.83 | NMT1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793862-B2 | Compositions and methods for modulating growth hormone receptor expression | IONIS PHARMACEUTICALS, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-20200123551-A1 | COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2020-04-23 | — | — | US | disclosed |