Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20643480 | 0.98 | SOAT1 (0.35) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL28155623 | 0.87 | ALDH1A1 (0.39) | CYP3A4ALDH1A1GAACES2 | |
| SCHEMBL11018811 | 0.83 | SOAT1 (0.36) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL2005556 | 0.80 | SOAT1 (0.33) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL11454255 | 0.78 | CES2 (0.52) | ALDH1A1DGKACES2 | |
| SCHEMBL7770132 | 0.78 | ALDH1A1 (0.54) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL5698083 | 0.78 | CES2 (0.52) | ALDH1A1DGKACES2 | |
| SCHEMBL18526280 | 0.78 | CES2 (0.52) | ALDH1A1DGKACES2 | |
| SCHEMBL13858877 | 0.78 | CES2 (0.52) | ALDH1A1DGKACES2 | |
| SCHEMBL7773634 | 0.78 | ALDH1A1 (0.54) | SOAT1MEN1FAAHTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793862-B2 | Compositions and methods for modulating growth hormone receptor expression | IONIS PHARMACEUTICALS, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-20200123551-A1 | COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2020-04-23 | — | — | US | disclosed |