Aconitic Acid

Aconitic Acid

SCHEMBL219037

O=C(O)/C=C(\CC(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 1.00
KDM4E B2RXH2 1/20 1.00
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 1/20 0.41
CPB1 P15086 1/20 0.41
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.33
ABAT P80404 1/20 0.31
GABRR1 P24046 2/20 0.31
GABRR2 P28476 2/20 0.31
BLM P54132 2/20 0.31
GABRR3 A8MPY1 1/20 0.31
LMNA P02545 1/20 0.31
APEX1 P27695 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aconitic Acid SCHEMBL1275978 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL16935 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL2022211 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL22334 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL1289876 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL29245497 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL9394649 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL27871922 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL30275008 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL27690462 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2400 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4486826-B1 TRANSFORMATION OF MYCELIUM INTO LEATHER, SKIN, HIDE AND/ OR TEXTILE SUBSTITUTE FRANCE CROCO (FR) 2026-05-27 EP claimed
WO-2026106451-A1 COMPOSITION WITH EFFICIENT LIQUID-ABSORPTION CAPACITY FOR VARIOUS USES AND METHOD FOR PRODUCING SAME MEINERS DE ALBA Andres (MX) 2026-05-21 WO claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-119570641-B Recombinant aspergillus niger strain for high production of trans-aconitic acid and application thereof 中国科学院青岛生物能源与过程研究所 2026-05-12 CN claimed
US-20260123372-A1 MANUFACTURING SEMICONDUCTOR DEVICE USING SELECTIVE DIELECTRIC ON DIELECTRIC (DOD) DEPOSITION PROCESS SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-04-30 US claimed
EP-4716622-A1 WOOD TREATMENT Ciol AS (NO) 2026-04-01 EP claimed
US-20260060970-A1 Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance MITODICURE GMBH (DE) 2026-03-05 US claimed
EP-4659591-A1 TASTE-ENHANCING COMPOSITION, METHOD FOR PRODUCING SAME, FOOD PRODUCT, AND METHOD FOR ENHANCING TASTE OF FOOD PRODUCT House Foods Group Inc. (JP) 2025-12-10 EP claimed
EP-4659592-A1 FLAVOR ENHANCING COMPOSITION, MANUFACTURING METHOD THEREFOR, AND METHOD FOR ENHANCING FLAVOR OF FOOD PRODUCT House Foods Corporation (JP) 2025-12-10 EP claimed
US-4936865-A POLYCARBOXYLIC ACID CROSSLINKERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1990-06-26 US claimed
EP-0354648-A2 Process for the formaldehyde-free durable press finishing of cotton textiles with polycarboxylic acids THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1990-02-14 EP claimed
US-4900730-A USING CHELATING AGENT AND SOLVENT; HIGH OSMOTIC PRESSURE TOYO JOZO CO., LTD. (JP) 1990-02-13 US claimed
WO-1989012714-A1 CATALYSTS AND PROCESSES FOR FORMALDEHYDE-FREE DURABLE PRESS FINISHING OF COTTON TEXTILES WITH POLYCARBOXYLIC ACIDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH (US) 1989-12-28 WO claimed
US-4853323-A ALSO CONTAINING A THIOCYANATE AND TRICARBOXYLIC ACID FOR INCREASED PHOTOSENSITIVITY TO LIGHT OF LOW ILLUMINATION FUJI PHOTO FILM CO., LTD. (JP) 1989-08-01 US claimed
US-4820307-A ALKALI METAL DIHYDROGEN PHOSPHATES AND SALTS OF PHOSPHOROUS, HYPOPHOSPHOROUS, AND POLYPHOSPHORIC ACIDS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1989-04-11 US claimed
US-4649199-A ANTITUMOR KYOWA HAKKO KOGYO CO., LTD. (JP) 1987-03-10 US claimed
EP-0157126-A1 A salt of DC-52 and a pharmaceutical composition containing the same KYOWA HAKKO KOGYO CO., LTD. (JP) 1985-10-09 EP claimed
US-4352758-A FROM TRANS-ACONITIC ACID HOFFMANN-LA ROCHE INC. (US) 1982-10-05 US claimed
US-4056567-A Chemical processes for preparing citric acid LEVER BROTHERS COMPANY (US) 1977-11-01 US claimed