Aconitic Acid

Aconitic Acid

SCHEMBL22334

O=C(O)C=C(CC(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 1.00
KDM4E B2RXH2 1/20 1.00
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 1/20 0.41
CPB1 P15086 1/20 0.41
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.33
ABAT P80404 1/20 0.31
GABRR1 P24046 2/20 0.31
GABRR2 P28476 2/20 0.31
BLM P54132 2/20 0.31
GABRR3 A8MPY1 1/20 0.31
LMNA P02545 1/20 0.31
APEX1 P27695 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aconitic Acid SCHEMBL1275978 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL16935 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL219037 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL2022211 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL1289876 1.00 TSHR (1.00) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL29245497 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL9394649 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL27871922 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL30275008 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15
Aconitic Acid SCHEMBL27690462 0.97 TSHR (0.95) TSHRKDM4ELDHASRRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 39231 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4486826-B1 TRANSFORMATION OF MYCELIUM INTO LEATHER, SKIN, HIDE AND/ OR TEXTILE SUBSTITUTE FRANCE CROCO (FR) 2026-05-27 EP claimed
CN-120623457-B Bio-based polyester polyol, preparation method thereof and application thereof in polyurethane material Henan Jinghui Polyurethane Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122060128-A Polycarboxylic acid water reducer based on photoinitiated polymerization, and preparation method and application thereof 安徽海螺材料科技股份有限公司 2026-05-19 CN claimed
WO-2026099250-A1 METHOD FOR THE PREPARATION OF ANHYDROUS THORIUM(IV) CHLORIDE THORIZON SASU (FR) 2026-05-15 WO claimed
WO-2026099446-A1 COMPOSITION AND PROCESS TO PREPARE A LIGNOCELLULOSIC-BASED ARTICLE EVERTREE (FR) 2026-05-15 WO claimed
EP-4739113-A1 COMPOSITION FOR USE IN AGRICULTURE Bayer Aktiengesellschaft (DE) 2026-05-13 EP claimed
EP-4741468-A1 COMPOSITION AND PROCESS TO PREPARE A LIGNOCELLULOSIC-BASED ARTICLE EVERTREE (FR) 2026-05-13 EP claimed
CN-119570641-B Recombinant aspergillus niger strain for high production of trans-aconitic acid and application thereof 中国科学院青岛生物能源与过程研究所 2026-05-12 CN claimed
WO-2026087758-A1 BIO-BASED POLYMERS CAMBRIUM GMBH (DE) 2026-04-30 WO claimed
US-20260123372-A1 MANUFACTURING SEMICONDUCTOR DEVICE USING SELECTIVE DIELECTRIC ON DIELECTRIC (DOD) DEPOSITION PROCESS SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-04-30 US claimed
US-4107121-A Ionogenic hydrophilic water-insoluble gels from partially hydrolyzed acrylonitrile polymers and copolymers, and a method of manufacturing same CESKOSLOVENSKA AKADEMIE VED (CS) 1978-08-15 US claimed
US-4089830-A ADHESIVES G-C DENTAL INDUSTRIAL CORP. (JA) 1978-05-16 US claimed
US-4014837-A BIS(HYDROCARBYL)VINYL PHOSPHONATES STAUFFER CHEMICAL COMPANY (US) 1977-03-29 US claimed
US-4000358-A ACRYLIC POLYMERSAMIDE ALELIO GAETANO F D 1976-12-28 US claimed
US-3998863-A ANTIOXIDANTS AMERICAN CYANAMID COMPANY (US) 1976-12-21 US claimed
US-3976614-A Inherrently water-dispersible, selfcrosslinking interpolymers useful as coatings THE DOW CHEMICAL COMPANY (US) 1976-08-24 US claimed
US-3959552-A Process for the production of cleaning-resistant nonwoven materials BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US claimed
US-3958026-A IODINE, POLYVINYLPYRROLIDONE CIBA-GEIGY CORPORATION (US) 1976-05-18 US claimed
US-3950392-A FIREPROOFING, HOMOPOLYMERIZATION, COPOLYMERIZATION ALELIO GAETANO F D 1976-04-13 US claimed
US-3935151-A Blended latex binder for exterior paints with wet primed adhesion BORDEN, INC. (US) 1976-01-27 US claimed