Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 9/20 | 0.43 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | ITK | Q08881 | 4/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21903619 | 0.97 | BTK (0.44) | KDRF10BTKRETROCK2 | |
| SCHEMBL21903622 | 0.97 | BTK (0.44) | KDRF10BTKRETROCK2 | |
| SCHEMBL21903685 | 0.95 | KDR (0.47) | KDRF10BTKRETROCK2 | |
| SCHEMBL31684291 | 0.91 | ROCK2 (0.44) | KDRBTKRETROCK2ROCK1 | |
| SCHEMBL21903773 | 0.91 | ROCK2 (0.44) | KDRBTKRETROCK2ROCK1 | |
| SCHEMBL21903684 | 0.91 | ROCK2 (0.44) | KDRBTKRETROCK2ROCK1 | |
| SCHEMBL21903683 | 0.88 | BTK (0.54) | BTKERBB2ERBB4 | |
| SCHEMBL21903745 | 0.88 | BTK (0.54) | BTKERBB2ERBB4 | |
| SCHEMBL21903688 | 0.88 | BTK (0.54) | BTKERBB2ERBB4 | |
| SCHEMBL21903576 | 0.85 | F10 (0.43) | KDRF10BTKRETROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180496-B2 | 1H-pyrazolopyridine derivative and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-11-23 | — | — | US | disclosed |
| US-20200140432-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180496-B2 | 1H-pyrazolopyridine derivative and pharmaceutical composition comprising the same | PDCD11, DPYD, G6PC1 | KDR 4166/4885F10 3239/4885BTK 1236/4885 |
| US-20200140432-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | PDCD11, G6PC1, PPM1D | KDR 4282/4885F10 3121/4885BTK 1744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.