Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium SCHEMBL30468551 | 0.98 | L3MBTL1 (0.63) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL29048025 | 0.98 | L3MBTL1 (0.63) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 | |
| Lithium Ion SCHEMBL21904259 | 0.84 | KMT2A (0.61) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL21904387 | 0.84 | KMT2A (0.61) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL1520499 | 0.84 | L3MBTL1 (0.61) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL3410537 | 0.83 | KMT2A (0.69) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL21904003 | 0.81 | KMT2A (0.55) | L3MBTL1KMT2ARAB9ANPC1CYP2D6 | |
| SCHEMBL31505932 | 0.80 | KMT2A (0.65) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL12424226 | 0.80 | KMT2A (0.65) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL7899244 | 0.79 | KMT2A (0.63) | L3MBTL1KMT2ARAB9ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110769821-B | Spiro indolines as IL-17 modulators | UCB生物制药有限责任公司 | 2023-07-07 | — | — | CN | disclosed |
| EP-3638227-B1 | SPIROCYCLIC INDOLINES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2022-08-10 | — | — | EP | disclosed |
| US-11052076-B2 | Spirocyclic indolines as IL-17 modulators | UCB Biopharma SRL (BE) | 2021-07-06 | — | — | US | disclosed |
| US-20200138797-A1 | Spirocyclic Indolines as IL-17 Modulators | UCB Biopharma SRL (BE) | 2020-05-07 | — | — | US | disclosed |
| CN-110769821-A | Spirocyclic indolines as IL-17 modulators | UCB生物制药私人有限公司 | 2020-02-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11052076-B2 | Spirocyclic indolines as IL-17 modulators | IL17A, IL2, IL18 | L3MBTL1 4331/4885KMT2A 2550/4885RAB9A 2204/4885 |
| US-20200138797-A1 | Spirocyclic Indolines as IL-17 Modulators | IL17A, IL2, IL18 | L3MBTL1 4331/4885KMT2A 2550/4885RAB9A 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.