Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21433613 | 1.00 | MAPT (0.59) | MAPTGAAKDM4EPOLBHTT | |
| SCHEMBL21433614 | 1.00 | MAPT (0.59) | MAPTGAAKDM4EPOLBHTT | |
| SCHEMBL21433615 | 0.78 | GAA (0.50) | MAPTGAAKDM4EPOLBHTT | |
| SCHEMBL21433602 | 0.75 | GAA (0.47) | MAPTGAAKDM4EPOLBHTT | |
| SCHEMBL21433603 | 0.75 | GAA (0.47) | MAPTGAAKDM4EPOLBHTT | |
| SCHEMBL21433599 | 0.73 | GAA (0.48) | MAPTGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL21433598 | 0.73 | GAA (0.48) | MAPTGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL12216548 | 0.73 | GAA (0.62) | MAPTGAAKDM4EPOLBMEN1 | |
| SCHEMBL1555835 | 0.71 | KDM4E (0.62) | MAPTGAAKDM4EPOLBMEN1 | |
| SCHEMBL1264279 | 0.71 | ALDH1A1 (0.69) | MAPTGAAKDM4EPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339272-B2 | Additive for rubber, rubber composition, and tire using the same | BRIDGESTONE CORPORATION (JP) | 2022-05-24 | — | — | US | disclosed |
| US-11339272-B2 | Additive for rubber, rubber composition, and tire using the same | BRIDGESTONE CORPORATION (JP) | 2022-05-24 | — | — | US | disclosed |
| US-20210171744-A1 | TIRE RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| US-20210108048-A1 | ADDITIVE FOR RUBBER, RUBBER COMPOSITION, AND TIRE USING THE SAME | BRIDGESTONE CORPORATION (JP) | 2021-04-15 | — | — | US | disclosed |
| US-20210108048-A1 | ADDITIVE FOR RUBBER, RUBBER COMPOSITION, AND TIRE USING THE SAME | BRIDGESTONE CORPORATION (JP) | 2021-04-15 | — | — | US | disclosed |
| US-20200109263-A1 | TIRE RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2020-04-09 | — | — | US | disclosed |
| EP-3549979-A1 | RUBBER ADDITIVE, RUBBER COMPOSITION, AND TIRE IN WHICH SAME IS USED | Bridgestone Corporation (JP) | 2019-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210108048-A1 | ADDITIVE FOR RUBBER, RUBBER COMPOSITION, AND TIRE USING THE SAME | HEATR1, HRH2, ATR | MAPT 3729/4885GAA 4469/4885KDM4E 3010/4885 |
| US-11339272-B2 | Additive for rubber, rubber composition, and tire using the same | HEATR1, HRH2, ATR | MAPT 3729/4885GAA 4469/4885KDM4E 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.