Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18581021 | 0.73 | SRC (0.48) | MAPTKDM4EMEN1KMT2ASRC | |
| Oxindole SCHEMBL1144643 | 0.69 | AHR (1.00) | PDK2AHRNPC1MAPTKDM4E | |
| Oxindole SCHEMBL19504 | 0.69 | AHR (1.00) | PDK2AHRNPC1MAPTKDM4E | |
| Oxindole SCHEMBL29358826 | 0.69 | AHR (1.00) | PDK2AHRNPC1MAPTKDM4E | |
| Oxindole SCHEMBL15636313 | 0.67 | AHR (0.95) | PDK2AHRNPC1MAPTKDM4E | |
| Oxindole SCHEMBL4720301 | 0.67 | AHR (0.95) | PDK2AHRNPC1MAPTKDM4E | |
| Oxindole SCHEMBL5668060 | 0.67 | AHR (0.95) | PDK2AHRNPC1MAPTKDM4E | |
| Oxindole SCHEMBL1462135 | 0.67 | AHR (0.95) | PDK2AHRNPC1MAPTKDM4E | |
| SCHEMBL1119036 | 0.67 | GAA (0.46) | PDK2AHRNPC1MAPTKDM4E | |
| Oxindole SCHEMBL5502064 | 0.67 | AHR (0.95) | PDK2AHRNPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021183707-A2 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES | FMC CORPORATION (US) | 2021-09-16 | — | — | WO | disclosed |
| WO-2020056090-A1 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES | FMC CORPORATION (US) | 2020-03-19 | — | — | WO | disclosed |