⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15950989 | 0.71 | COMT (0.60) | — | |
| SCHEMBL28593290 | 0.71 | COMT (0.44) | — | |
| SCHEMBL3489735 | 0.67 | CYP1A2 (0.53) | — | |
| SCHEMBL28168867 | 0.67 | — | — | |
| SCHEMBL22334277 | 0.67 | — | — | |
| SCHEMBL1085994 | 0.67 | — | — | |
| SCHEMBL27273506 | 0.67 | — | — | |
| SCHEMBL31148036 | 0.67 | ALDH1A1 (0.41) | — | |
| SCHEMBL2125364 | 0.67 | — | — | |
| SCHEMBL294934 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222739-B | Sulfonylurea derivatives and their use | 诺瑟拉有限公司 | 2025-02-11 | — | — | CN | disclosed |
| WO-2023215801-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| EP-3983402-B1 | 1-((S)-1-(3-CHLORO-5-FLUORO-2-((4-(1H-PYRAZOL-1-YL)-2-METHYLQUINOLIN-8-YLOXY)METHYL)PHENYL)ETHYL)-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ (BK) B2 RECEPTOR ANTAGONIST FOR TREATING SKIN DISEASES | PHARVARIS GMBH (CH) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022217070-A1 | HGF/SF MIMETIC COMPOUNDS | ANGION BIOMEDICA CORP. (US) | 2022-10-13 | — | — | WO | disclosed |
| CN-114222739-A | Sulfonylurea derivatives and use thereof | 诺瑟拉有限公司 | 2022-03-22 | — | — | CN | disclosed |
| US-20210017158-A1 | NOVEL BRADYKININ B2 RECEPTOR ANTAGONISTS | ANALYTICON DISCOVERY GMBH (DE) | 2021-01-21 | — | — | US | disclosed |
| WO-2020234479-A1 | 1-((S)-1-(3-CHLORO-5-FLUORO-2-((4-(1H-PYRAZOL-1-YL)-2-METHYLQUINOLIN-8-YLOXY)METHYL)PHENYL)ETHYL)-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ (BK) B2 RECEPTOR ANTAGONIST FOR TREATING SKIN DISEASES | PHARVARIS GMBH (CH) | 2020-11-26 | — | — | WO | disclosed |
| US-10349658-B2 | Method for treating coffee rust, citrus black spot, citrus scab and banana black sigatoka diseases | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-16 | — | — | US | disclosed |
| US-20180153169-A1 | METHOD FOR TREATING COFFEE RUST, CITRUS BLACK SPOT, CITRUS SCAB AND BANANA BLACK SIGATOKA DISEASES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-07 | — | — | US | disclosed |
| CN-102977029-B | As 5 HT2ASerotonin receptor modulator is applied to treat 3 phenylpyrazole derivatives of relative illness | 艾尼纳制药公司 | 2017-12-19 | — | — | CN | disclosed |
| US-20110177950-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing the Same | BASF SE (DE) | 2011-07-21 | — | — | US | disclosed |
| US-20110172095-A1 | Triazole Compounds, Use Thereof and Agents Containing Same | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| US-20090048306-A1 | PYRIDINE DERIVATIVES | PFIZER, INC. (US) | 2009-02-19 | — | — | US | disclosed |