Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15699637 | 0.94 | CALCRL (0.31) | — | |
| SCHEMBL17524917 | 0.87 | EGLN1 (0.33) | DGAT1 | |
| SCHEMBL21912460 | 0.86 | NPC1 (0.30) | — | |
| SCHEMBL722670 | 0.86 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL15882578 | 0.86 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL15699763 | 0.85 | NAMPT (0.37) | — | |
| SCHEMBL3705563 | 0.81 | RAMP1 (0.31) | — | |
| SCHEMBL6349241 | 0.81 | NPC1 (0.31) | — | |
| SCHEMBL18181139 | 0.80 | EGLN1 (0.39) | — | |
| SCHEMBL15095536 | 0.78 | P2RY12 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632910-A1 | LACTAM COMPOUND AS FXR RECEPTOR AGONIST | Medshine Discovery Inc. (CN) | 2020-04-08 | — | — | EP | disclosed |