Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17524871 | 0.89 | OPRM1 (0.33) | — | |
| SCHEMBL21912465 | 0.87 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL17506487 | 0.85 | NPC1 (0.34) | — | |
| SCHEMBL17525045 | 0.85 | EGLN1 (0.41) | EGLN1 | |
| SCHEMBL15699637 | 0.85 | CALCRL (0.31) | — | |
| SCHEMBL17506429 | 0.80 | GAA (0.37) | — | |
| SCHEMBL15699763 | 0.79 | NAMPT (0.37) | — | |
| SCHEMBL17525046 | 0.77 | OPRL1 (0.35) | EGLN1 | |
| SCHEMBL722670 | 0.76 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL15882578 | 0.76 | DGAT1 (0.32) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022644-A1 | HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2016-02-11 | — | — | WO | disclosed |