Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22435817 | 0.79 | EYA3 (0.43) | ALDH1A1LMNAMAPTSLC22A12EYA3 | |
| SCHEMBL28183947 | 0.76 | KCNH2 (0.45) | ALPGNQO1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL21883464 | 0.75 | MAPT (0.39) | ALPGNQO1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18574501 | 0.75 | ALPG (0.39) | ALPGNQO1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23652520 | 0.74 | CYP2D6 (0.36) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MAPT | |
| SCHEMBL31217594 | 0.71 | ALPG (0.48) | ALPGNQO1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24884759 | 0.71 | ACP1 (0.36) | ALDH1A1L3MBTL1SLC22A12KDM4E | |
| SCHEMBL21201756 | 0.70 | MAPT (0.42) | ALPGNQO1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23665435 | 0.70 | MAPT (0.52) | ALPGNQO1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24611425 | 0.68 | MCL1 (0.38) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640252-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2020-04-22 | — | — | EP | disclosed |