SCHEMBL21883464

SCHEMBL21883464

C=Cc1c(/C=C\C)oc2ccc(C)cc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.39
ALPG P10696 1/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 5/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.35
KDM4E B2RXH2 7/20 0.34
HPGD P15428 3/20 0.34
CYP3A4 P08684 3/20 0.34
TP53 P04637 2/20 0.34
HSD17B10 Q99714 2/20 0.34
NQO1 P15559 1/20 0.34
MAPK1 P28482 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
AKR1B1 P15121 1/20 0.33
PTGES O14684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18574501 0.88 ALPG (0.39) MAPTALPGATMALDH1A1SMN1; SMN2
SCHEMBL26840950 0.88 MAOB (0.36) MAPTALPGATMALDH1A1HPGD
SCHEMBL20724987 0.83 SMN1; SMN2 (0.41) MAPTALPGALDH1A1SMN1; SMN2KDM4E
SCHEMBL20028573 0.83 KDM4E (0.30) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL19119672 0.83 PIM1 (0.36) MAPTSMN1; SMN2LMNAKDM4ECYP3A4
SCHEMBL21201756 0.80 MAPT (0.42) MAPTALPGATMALDH1A1SMN1; SMN2
SCHEMBL17192976 0.79 L3MBTL1 (0.37) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL24086789 0.77 ELANE (0.33) ATMMEN1KMT2A
SCHEMBL21517327 0.76 PLA2G2A (0.33) MAPTATMALDH1A1SMN1; SMN2KDM4E
SCHEMBL14327643 0.75 MAOB (0.36) ALPGALDH1A1HPGDTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374049-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-23 US disclosed
US-11780866-B2 Organometallic compound, organic light-emitting device including organometallic compound, and diagnostic composition including organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-10 US disclosed
US-20210155647-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-27 US disclosed
US-20200283463-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-09-10 US disclosed
US-20200099001-A1 ORGANIC LIGHT-EMITTING DEVICE, APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283463-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, AP1M1, FOXM1 MAPT 670/4885ALPG 3231/4885ATM 2180/4885
US-20230374049-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND NOM1, MSL1, L1CAM MAPT 990/4885ALPG 2559/4885ATM 1430/4885
US-20200099001-A1 ORGANIC LIGHT-EMITTING DEVICE, APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND LEF1, OCIAD1, OXA1L MAPT 1710/4885ALPG 1324/4885ATM 3270/4885
US-20210155647-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND NOM1, MSL1, L1CAM MAPT 990/4885ALPG 2559/4885ATM 1430/4885
US-11780866-B2 Organometallic compound, organic light-emitting device including organometallic compound, and diagnostic composition including organometallic compound NOM1, MSL1, L1CAM MAPT 990/4885ALPG 2559/4885ATM 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.