SCHEMBL21912936

SCHEMBL21912936

CCCC1Cc2ccccc2N(C)[C@H]1C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRKCD Q05655 5/20 0.41
HTR1A P08908 2/20 0.39
PKM P14618 1/20 0.39
NOTUM Q6P988 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
PRKCG P05129 1/20 0.37
PRKCA P17252 1/20 0.37
OPRM1 P35372 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7067724 0.79 MTNR1A (0.43) PRKCDPKMPRKCGPRKCAALDH1A1
SCHEMBL21172504 0.77 NOTUM (0.43) PRKCDNOTUMPRKCGPRKCAOPRM1
SCHEMBL21172724 0.77 NOTUM (0.43) PRKCDNOTUMPRKCGPRKCAOPRM1
SCHEMBL787596 0.77 NOTUM (0.43) PRKCDNOTUMPRKCGPRKCAOPRM1
SCHEMBL21172759 0.75 PRKCD (0.38) PRKCDNOTUMPRKCGPRKCA
SCHEMBL12340979 0.74 NOTUM (0.41) PRKCDNOTUMPRKCGPRKCAOPRM1
SCHEMBL31672940 0.72 NOTUM (0.55) PKMNOTUMCHRM2CHRM4CHRM1
SCHEMBL6890897 0.72 NOTUM (0.55) PKMNOTUMCHRM2CHRM4CHRM1
SCHEMBL7733992 0.72 NOTUM (0.55) PKMNOTUMCHRM2CHRM4CHRM1
SCHEMBL811795 0.72 NOTUM (0.55) PKMNOTUMCHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3640252-A1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS UDC Ireland Limited (IE) 2020-04-22 EP disclosed