Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21912818 | 0.74 | ALOX5 (0.46) | ALOX5NQO1MAPTHPGDKDM4E | |
| SCHEMBL17057177 | 0.74 | PRKDC (0.44) | ALOX5NQO1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL20960207 | 0.74 | MCL1 (0.39) | ALDH1A1 | |
| SCHEMBL21913228 | 0.70 | ALOX5 (0.44) | ALOX5NQO1PGRMAPTHPGD | |
| SCHEMBL4431843 | 0.68 | MCL1 (0.45) | MAPTHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21912961 | 0.68 | — | — | |
| SCHEMBL21913987 | 0.67 | — | — | |
| SCHEMBL21742675 | 0.67 | ALOX5 (0.49) | ALOX5NQO1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL23581451 | 0.67 | ALDH1A1 (0.57) | PGRMAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL23439843 | 0.66 | KDM4E (0.35) | NQO1MAPTHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640252-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2020-04-22 | — | — | EP | disclosed |