Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999764 | 0.90 | ACHE (0.47) | ACHEHTR2AHTR2CGPR3MAOA | |
| SCHEMBL15722716 | 0.80 | GPR3 (0.48) | ACHEHTR2AHTR2CGPR3MAOA | |
| SCHEMBL22044320 | 0.78 | HPGD (0.47) | ACHEHTR2AHTR2CGPR3MAOA | |
| SCHEMBL24531884 | 0.77 | GPR3 (0.42) | ACHEHTR2AHTR2CGPR3MAOA | |
| SCHEMBL21913127 | 0.74 | HTR2A (0.43) | HTR2AHTR2CGPR3KDM4EALOX15 | |
| SCHEMBL15128345 | 0.74 | GPR3 (0.39) | ACHEHTR2AHTR2CGPR3MAOA | |
| SCHEMBL22298378 | 0.73 | GPR3 (0.45) | ACHEHTR2AHTR2CGPR3MAOA | |
| SCHEMBL14133187 | 0.71 | GPR3 (0.40) | ACHEHTR2AHTR2CGPR3MAOA | |
| SCHEMBL20824722 | 0.71 | HTR2A (0.43) | ACHEHTR2AHTR2CGPR3MAOA | |
| SCHEMBL25638913 | 0.71 | PDE5A (0.43) | MAOAKDM4EALOX15MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640252-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2020-04-22 | — | — | EP | disclosed |