Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21914560 | 0.82 | MAPT (0.53) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL28542942 | 0.73 | ALDH1A1 (0.86) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL14433882 | 0.73 | ALDH1A1 (0.86) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL16562244 | 0.71 | RAB9A (0.74) | ALDH1A1MAPTSMN1; SMN2GAAMEN1 | |
| SCHEMBL3593541 | 0.70 | NPSR1 (0.57) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL23319960 | 0.69 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL16562183 | 0.69 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL3822991 | 0.67 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAHTTGAA | |
| SCHEMBL18894145 | 0.67 | ALDH1A1 (0.73) | ALDH1A1MAPTLMNAHTTMEN1 | |
| SCHEMBL7894076 | 0.67 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640253-A1 | 6H-THIENO[2,3-E][1,2,4]TRIAZOLO[3,4-C][1,2,4]TRIAZEPINE DERIVATIVE | AYUMI Pharmaceutical Corporation (JP) | 2020-04-22 | — | — | EP | disclosed |