Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP3 | P08254 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23235630 | 1.00 | BIRC2 (0.73) | BIRC2RECQLMEN1HPGDKMT2A | |
| SCHEMBL20991859 | 1.00 | BIRC2 (0.73) | BIRC2RECQLMEN1HPGDKMT2A | |
| SCHEMBL23801208 | 0.86 | BIRC2 (0.64) | BIRC2RECQLMEN1KMT2AUSP2 | |
| SCHEMBL8373232 | 0.85 | BIRC2 (0.58) | BIRC2RECQLHSD17B10USP2CA2 | |
| SCHEMBL24961565 | 0.83 | BIRC2 (0.54) | BIRC2RECQLMEN1HPGDKMT2A | |
| SCHEMBL5258058 | 0.82 | FAAH (0.57) | BIRC2LMNACA2MMP2MMP3 | |
| SCHEMBL28399284 | 0.81 | BIRC2 (0.55) | BIRC2ZDHHC7USP2LMNACA2 | |
| SCHEMBL5262130 | 0.81 | FAAH (0.55) | BIRC2CA2CA1MMP2MMP3 | |
| SCHEMBL5108907 | 0.80 | BIRC2 (0.57) | BIRC2RECQLHPGDUSP2LMNA | |
| SCHEMBL5108904 | 0.80 | BIRC2 (0.57) | BIRC2RECQLHPGDUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633371-B2 | EZH2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633371-B2 | EZH2 inhibitors and uses thereof | EZH2, EZH1, BMI1 | BIRC2 1925/4885RECQL 2581/4885MEN1 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.