SCHEMBL21914810

SCHEMBL21914810

FC1(c2n[nH]c(-c3ccc(OCc4ccccc4)cc3)n2)CC1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 13/20 0.46
DHODH Q02127 2/20 0.45
IKBKE Q14164 1/20 0.44
PTGES O14684 1/20 0.42
ALOX5 P09917 1/20 0.42
LTC4S Q16873 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23590409 0.79 PRMT5 (0.45) PRMT5DHODHIKBKEPTGESALOX5
SCHEMBL21889265 0.78 AOC3 (0.59) PRMT5DHODHIKBKENPC1RAB9A
SCHEMBL21914562 0.76 PRMT5 (0.49) PRMT5DHODHIKBKEPTGESALOX5
SCHEMBL21889198 0.75 PRMT5 (0.57) PRMT5IKBKEPTGESALOX5LTC4S
SCHEMBL21889308 0.74 PRMT5 (0.47) PRMT5DHODHIKBKEPTGESALOX5
SCHEMBL25836249 0.73 IKBKE (0.50) PRMT5DHODHIKBKEPTGESALOX5
SCHEMBL21914803 0.73 PRMT5 (0.52) PRMT5IKBKEPTGESALOX5LTC4S
SCHEMBL21914579 0.73 PRMT5 (0.52) PRMT5IKBKEPTGESALOX5LTC4S
SCHEMBL21914361 0.72 CHEK2 (0.56) PRMT5DHODHIKBKE
SCHEMBL21889536 0.71 PRMT5 (0.47) PRMT5DHODHIKBKEPTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626699-A1 SSAO INHIBITOR Shandong Danhong Pharmaceutical Co., Ltd. (CN) 2020-03-25 EP disclosed