Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 12/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21889308 | 0.77 | PRMT5 (0.47) | IKBKEPRMT5NPC1RAB9AL3MBTL1 | |
| SCHEMBL21914562 | 0.76 | PRMT5 (0.49) | IKBKEPRMT5NPC1RAB9AL3MBTL1 | |
| SCHEMBL21889198 | 0.75 | PRMT5 (0.57) | IKBKEPRMT5PTGESALOX5LTC4S | |
| SCHEMBL21914361 | 0.74 | CHEK2 (0.56) | IKBKEPRMT5DHODH | |
| SCHEMBL25836250 | 0.74 | AOC3 (0.55) | IKBKEPRMT5NPC1RAB9AL3MBTL1 | |
| SCHEMBL21914803 | 0.73 | PRMT5 (0.52) | IKBKEPRMT5PTGESALOX5LTC4S | |
| SCHEMBL21914810 | 0.73 | PRMT5 (0.46) | IKBKEPRMT5NPC1RAB9AL3MBTL1 | |
| SCHEMBL21914579 | 0.73 | PRMT5 (0.52) | IKBKEPRMT5PTGESALOX5LTC4S | |
| SCHEMBL12732314 | 0.72 | APP (0.63) | RAB9AL3MBTL1ENPP3ENPP1TP53 | |
| SCHEMBL23590409 | 0.72 | PRMT5 (0.45) | IKBKEPRMT5NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626699-B1 | SSAO INHIBITOR | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2023-07-12 | — | — | EP | disclosed |