Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915549 | 0.85 | HSD17B1 (0.41) | HSD17B1HSD17B2POLBMAPTSNCA | |
| SCHEMBL21915204 | 0.85 | HSD17B1 (0.38) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21916418 | 0.84 | HSD17B1 (0.44) | HSD17B1HSD17B2POLBMAPTSNCA | |
| SCHEMBL21915853 | 0.84 | HSD17B1 (0.40) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915844 | 0.81 | HSD17B1 (0.47) | HSD17B1HSD17B2POLBMAPTSNCA | |
| SCHEMBL21915515 | 0.81 | HSD17B1 (0.39) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915470 | 0.80 | HSD17B1 (0.54) | HSD17B1HSD17B2POLBMAPTSNCA | |
| SCHEMBL21915542 | 0.79 | PDE6D (0.39) | HSD17B1HSD17B2POLBMAPTCYP19A1 | |
| SCHEMBL21915268 | 0.78 | HSD17B1 (0.49) | HSD17B1HSD17B2POLBMAPTSNCA | |
| SCHEMBL21915834 | 0.78 | HSD17B1 (0.51) | HSD17B1HSD17B2MAPTSNCACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |