Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915391 | 0.89 | HSD17B1 (0.39) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915551 | 0.86 | HSD17B1 (0.47) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915470 | 0.85 | HSD17B1 (0.54) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915469 | 0.85 | HSD17B1 (0.43) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915545 | 0.85 | HSD17B1 (0.46) | HSD17B1HSD17B2PDE6DMAPTSNCA | |
| SCHEMBL21915834 | 0.83 | HSD17B1 (0.51) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21916418 | 0.83 | HSD17B1 (0.44) | HSD17B1HSD17B2PDE6DMAPTSNCA | |
| SCHEMBL21915839 | 0.82 | HSD17B1 (0.48) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915522 | 0.82 | HSD17B1 (0.41) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915268 | 0.81 | HSD17B1 (0.49) | HSD17B1HSD17B2MAPTSNCACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |