Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | BMX | P51813 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.30 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.30 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915888 | 0.89 | HSD17B1 (0.39) | HSD17B1HSD17B2FLT3BMXTUBB4A | |
| SCHEMBL21915522 | 0.86 | HSD17B1 (0.41) | HSD17B1HSD17B2KDM4EATML3MBTL1 | |
| SCHEMBL21916412 | 0.86 | HDAC8 (0.33) | FLT3BMXTUBB4ATUBBTUBA3C | |
| SCHEMBL21915183 | 0.83 | HSD17B1 (0.35) | HSD17B1HSD17B2KDM4EATML3MBTL1 | |
| SCHEMBL21915859 | 0.82 | HSD17B1 (0.39) | HSD17B1HSD17B2KDM4EATML3MBTL1 | |
| SCHEMBL21915249 | 0.81 | HSD17B1 (0.37) | HSD17B1HSD17B2KDM4EMAPTSNCA | |
| SCHEMBL21915458 | 0.81 | HSD17B1 (0.37) | HSD17B1HSD17B2FLT3TUBB4ATUBB | |
| SCHEMBL17640486 | 0.79 | HSD17B1 (0.52) | HSD17B1HSD17B2KDM4EATML3MBTL1 | |
| SCHEMBL20291236 | 0.79 | KDM4E (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21915289 | 0.79 | HSD17B1 (0.46) | HSD17B1HSD17B2KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |