Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915594 | 0.90 | ALOX5 (0.36) | ALOX5PDE6DMAPTTSHRMEN1 | |
| SCHEMBL21915536 | 0.82 | ALOX5 (0.35) | ALOX5CYP1A2CYP2C9CYP2C19PRKDC | |
| SCHEMBL21915588 | 0.82 | ALOX5 (0.33) | ALOX5CYP1A2CYP2C9CYP2C19PRKDC | |
| SCHEMBL15470327 | 0.82 | ALOX5 (0.51) | ALOX5PDE6DTSHRCYP1A2CYP3A4 | |
| SCHEMBL21915240 | 0.79 | ALOX5 (0.35) | ALOX5PRKDCPIK3CDPIK3CB | |
| SCHEMBL21915244 | 0.79 | ALOX5 (0.35) | ALOX5PRKDCPIK3CDPIK3CB | |
| SCHEMBL21915846 | 0.79 | ALOX5 (0.44) | ALOX5MAPTMEN1KMT2AKDM4E | |
| SCHEMBL21915543 | 0.78 | PTGER4 (0.37) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17278624 | 0.78 | ALOX5 (0.41) | ALOX5PDE6DMAPTTSHRMEN1 | |
| SCHEMBL17278616 | 0.78 | ALOX5 (0.39) | ALOX5PDE6DMAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |