Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915536 | 0.87 | ALOX5 (0.35) | ALOX5NPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21915594 | 0.86 | ALOX5 (0.36) | ALOX5CYP1A2CYP2C9CYP2C19PRKDC | |
| SCHEMBL21915850 | 0.82 | ALOX5 (0.38) | ALOX5CYP1A2CYP2C9CYP2C19PRKDC | |
| SCHEMBL21915580 | 0.81 | ALOX5 (0.39) | ALOX5PRKDC | |
| SCHEMBL21915584 | 0.81 | HSD17B1 (0.31) | — | |
| SCHEMBL15470296 | 0.79 | ALOX5 (0.44) | ALOX5CYP1A2CYP2C9CYP2C19PRKDC | |
| SCHEMBL21915419 | 0.79 | HSD17B1 (0.38) | BCHE | |
| SCHEMBL21915577 | 0.78 | MAPT (0.36) | — | |
| SCHEMBL17278616 | 0.77 | ALOX5 (0.39) | ALOX5NPC1RAB9APRKDC | |
| SCHEMBL17278624 | 0.77 | ALOX5 (0.41) | ALOX5PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |