Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | PDE8A | O60658 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
| ▸ | PDE6A | P16499 | 1/20 | 0.38 |
| ▸ | PDE6G | P18545 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE6B | P35913 | 1/20 | 0.38 |
| ▸ | PDE6C | P51160 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21918497 | 0.92 | PDE2A (0.45) | PDE3BPDE3APDE2APDE6DPDE8A | |
| SCHEMBL12759645 | 0.82 | PDE3B (0.49) | PDE3BPDE3APDE2APDE6DPDE8A | |
| SCHEMBL21918453 | 0.80 | KDM4E (0.39) | PDE3BPDE3APDE2APDE6DPDE8A | |
| SCHEMBL21298336 | 0.80 | PDE3B (0.35) | PDE3BPDE3APDE2APDE6DPDE8A | |
| SCHEMBL23948351 | 0.80 | PDE2A (0.47) | PDE3BPDE3APDE2APDE6DPDE8A | |
| SCHEMBL840406 | 0.74 | MAPK8 (0.41) | PDE3BPDE3APDE2APDE6DPDE8A | |
| SCHEMBL29636632 | 0.74 | MAPK8 (0.41) | PDE3BPDE3APDE2APDE6DPDE8A | |
| SCHEMBL21917513 | 0.74 | KDM4E (0.38) | CDK2ROCK1DYRK1ADYRK1BALDH1A1 | |
| SCHEMBL24291715 | 0.73 | LIMK1 (0.35) | PDE3BPDE3APDE2APDE6DPDE8A | |
| SCHEMBL16193836 | 0.73 | MAPK8 (0.40) | PDE3BPDE3APDE2APDE6DPDE8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11063228-B2 | Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200119288-A1 | Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues | UNITED STATES DEPARTMENT OF ENERGY | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200119288-A1 | Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues | IK, HELZ, SUN2 | PDE3B 4066/4885PDE3A 3495/4885PDE2A 3593/4885 |
| US-11063228-B2 | Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues | IK, HELZ, SUN2 | PDE3B 4066/4885PDE3A 3495/4885PDE2A 3593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.