Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | FABP7 | O15540 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190862 | 0.94 | CASP1 (0.41) | CASP1FABP5FABP7BACE1EPHX2 | |
| SCHEMBL25968658 | 0.90 | CASP1 (0.42) | CASP1FABP5FABP7BACE1EPHX2 | |
| SCHEMBL25344517 | 0.90 | CASP1 (0.42) | CASP1FABP5FABP7BACE1EPHX2 | |
| SCHEMBL25344362 | 0.90 | CASP1 (0.42) | CASP1FABP5FABP7BACE1EPHX2 | |
| SCHEMBL25345345 | 0.90 | CASP1 (0.42) | CASP1FABP5FABP7BACE1EPHX2 | |
| SCHEMBL26184776 | 0.81 | FABP5 (0.40) | FABP5FABP7EPHX2KMT2AGRM2 | |
| SCHEMBL25968400 | 0.80 | CASP1 (0.40) | CASP1FABP5FABP7BACE1EPHX2 | |
| SCHEMBL4600775 | 0.77 | FABP5 (0.42) | FABP5FABP7EPHX2KMT2AGRM2 | |
| SCHEMBL25968518 | 0.76 | CASP1 (0.39) | CASP1FABP5FABP7BACE1EPHX2 | |
| SCHEMBL28864147 | 0.76 | EPHX2 (0.44) | FABP5FABP7EPHX2KMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978371-B | Polypeptide derivative and application thereof in field of medicine | 成都诺和晟泰生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-111978371-A | Polypeptide derivative and application thereof in field of medicine | 成都诺和晟泰生物科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| US-20110172126-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2011-07-14 | — | — | US | disclosed |