Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344362 | 1.00 | CASP1 (0.42) | CASP1GRM2GRM3GRM6FABP5 | |
| SCHEMBL25344517 | 1.00 | CASP1 (0.42) | CASP1GRM2GRM3GRM6FABP5 | |
| SCHEMBL25345345 | 1.00 | CASP1 (0.42) | CASP1GRM2GRM3GRM6FABP5 | |
| SCHEMBL2191771 | 0.90 | CASP1 (0.41) | CASP1GRM2GRM3GRM6FABP5 | |
| SCHEMBL25968400 | 0.85 | CASP1 (0.40) | CASP1FABP5FABP7EPHX2KMT2A | |
| SCHEMBL2190862 | 0.84 | CASP1 (0.41) | CASP1GRM2GRM3FABP5FABP7 | |
| SCHEMBL12464643 | 0.84 | GRM6 (0.46) | CASP1GRM2GRM3GRM6 | |
| SCHEMBL25968518 | 0.82 | CASP1 (0.39) | CASP1FABP5FABP7EPHX2KMT2A | |
| SCHEMBL25968404 | 0.81 | CASP1 (0.37) | CASP1FABP5FABP7EPHX2KMT2A | |
| SCHEMBL25968407 | 0.81 | CASP1 (0.37) | CASP1FABP5FABP7EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |