Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 19/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194864 | 0.92 | FAAH (0.64) | FAAH | |
| SCHEMBL2193500 | 0.88 | FAAH (0.68) | FAAHCYP2D6 | |
| SCHEMBL2193495 | 0.87 | FAAH (0.67) | FAAHCYP2D6SMN1; SMN2 | |
| SCHEMBL2196594 | 0.84 | FAAH (0.72) | FAAHCYP2D6 | |
| SCHEMBL13806645 | 0.83 | FAAH (0.76) | FAAHCYP2D6SMN1; SMN2 | |
| SCHEMBL12509039 | 0.82 | FAAH (0.68) | FAAH | |
| SCHEMBL12509208 | 0.82 | FAAH (0.69) | FAAHMEN1ALDH1A1KMT2A | |
| SCHEMBL2191748 | 0.82 | FAAH (0.65) | FAAHCYP2D6 | |
| SCHEMBL2194619 | 0.82 | FAAH (0.67) | FAAH | |
| SCHEMBL2194615 | 0.81 | FAAH (0.64) | FAAHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | FAAH 1/4885CYP2D6 3951/4885MEN1 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.