Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21921818 | 0.89 | ACACB (0.31) | — | |
| SCHEMBL8055365 | 0.81 | L3MBTL1 (0.40) | L3MBTL1CACNA1ICACNA1GCACNA1HCNR2 | |
| SCHEMBL22811190 | 0.81 | L3MBTL1 (0.40) | L3MBTL1CACNA1ICACNA1GCACNA1HCNR2 | |
| Hydrochloric Acid SCHEMBL3037901 | 0.79 | L3MBTL1 (0.39) | L3MBTL1CACNA1ICACNA1GCACNA1HCNR2 | |
| SCHEMBL3038285 | 0.79 | CACNA1G (0.33) | L3MBTL1CACNA1ICACNA1GCACNA1HCNR2 | |
| SCHEMBL4550831 | 0.77 | L3MBTL1 (0.47) | L3MBTL1CACNA1ICACNA1GCACNA1HCNR2 | |
| SCHEMBL21600651 | 0.77 | CACNA1I (0.58) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| Hydrochloric Acid SCHEMBL2719306 | 0.76 | L3MBTL1 (0.46) | L3MBTL1CACNA1ICACNA1GCACNA1HCNR2 | |
| SCHEMBL24468106 | 0.75 | CYP2D6 (0.35) | CYP2C19CYP2C9 | |
| SCHEMBL27180483 | 0.75 | CYP2D6 (0.35) | CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632899-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RaQualia Pharma Inc. (JP) | 2020-04-08 | — | — | EP | disclosed |