Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17240403 | 0.70 | RAB9A (0.54) | KMT2ALMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL2132615 | 0.70 | HTR2A (0.44) | KCNH2HTR2ACYP1A2CYP2C19HTR2C | |
| SCHEMBL2133636 | 0.69 | RAB9A (0.56) | MEN1KMT2ALMNASMN1; SMN2EPHX2 | |
| SCHEMBL2137443 | 0.67 | NOTUM (0.47) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL21921792 | 0.67 | HTR2A (0.42) | MEN1KMT2AHTR2ACYP1A2TRPV1 | |
| SCHEMBL2137785 | 0.67 | HTT (0.47) | KMT2AHTR2CMAPTHTTSMN1; SMN2 | |
| SCHEMBL2137173 | 0.67 | EPHX2 (0.54) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL2136526 | 0.66 | EPHX2 (0.52) | MEN1KMT2ATRPV1SMN1; SMN2EPHX2 | |
| SCHEMBL2143239 | 0.66 | ALDH1A1 (0.53) | KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL10256966 | 0.65 | CACNA1I (0.51) | KCNH2CACNA1GCACNA1HCACNA1ICNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632899-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RaQualia Pharma Inc. (JP) | 2020-04-08 | — | — | EP | disclosed |