SCHEMBL21921970

SCHEMBL21921970

CC1=CC(c2c(C)cc(O)c(C3C=C(C)CCC3)c2N=O)CCC1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 1/20 0.36
CNR1 P21554 4/20 0.33
CNR2 P34972 3/20 0.32
OPRM1 P35372 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22430730 0.78 GPR55 (0.52) GPR55CNR1CNR2OPRM1
SCHEMBL23948549 0.78 GPR55 (0.52) GPR55CNR1CNR2OPRM1
SCHEMBL22705363 0.76 GPR55 (0.46) GPR55CNR1CNR2OPRM1
SCHEMBL31545325 0.76 GPR55 (0.46) GPR55CNR1CNR2OPRM1
SCHEMBL18386358 0.76 CNR1 (0.49) GPR55CNR1CNR2OPRM1
SCHEMBL22537449 0.76 CNR1 (0.49) GPR55CNR1CNR2OPRM1
SCHEMBL18386376 0.74 GPR55 (0.35) GPR55CNR1CNR2OPRM1
SCHEMBL24525885 0.73 CNR1 (0.37) GPR55CNR1CNR2OPRM1
SCHEMBL23587290 0.71 CNR1 (0.33) GPR55CNR1CNR2OPRM1
SCHEMBL26231149 0.70 CNR2 (0.50) GPR55CNR1CNR2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3643697-A1 TREATMENT METHOD, COMPOUNDS, AND METHOD OF INCREASING TRPV2 ACTIVITY The Feinstein Institute for Medical Research (US) 2020-04-29 EP disclosed