Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783352 | 0.98 | CLK4 (0.53) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16940443 | 0.88 | CLK4 (0.43) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL26910409 | 0.88 | CLK4 (0.52) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29358412 | 0.85 | — | — | |
| SCHEMBL99039 | 0.85 | — | — | |
| Water SCHEMBL27994505 | 0.85 | ENPP2 (0.48) | CLK4IDO1MAOB | |
| SCHEMBL2154026 | 0.85 | CLK4 (0.65) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30839882 | 0.84 | CYP11B2 (0.47) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL5553903 | 0.84 | CYP11B2 (0.47) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL3988152 | 0.84 | CLK4 (0.52) | CLK4GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3644385-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | Samsung Electronics Co., Ltd. (KR) | 2020-04-29 | — | — | EP | disclosed |