SCHEMBL21922671

SCHEMBL21922671

CP(=O)(c1ccccc1)c1ccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.53
HPGD P15428 1/20 0.45
ACHE P22303 6/20 0.42
LMNA P02545 2/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA5A P35218 1/20 0.37
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
MAP2 P11137 1/20 0.35
PTGS2 P35354 1/20 0.35
ESR2 Q92731 2/20 0.34
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21922669 0.98 ESR1 (0.52) ESR1HPGDACHELMNAMAPT
SCHEMBL21922968 0.98 ESR1 (0.52) ESR1HPGDACHELMNAMAPT
SCHEMBL21922670 0.90 ESR1 (0.44) ESR1HPGDACHECA2
SCHEMBL21922948 0.88 ESR1 (0.43) ESR1HPGDACHELMNACA2
SCHEMBL18893041 0.88 ACHE (0.42) ESR1ACHELMNAMAPTHTT
SCHEMBL21922964 0.87 ESR1 (0.42) ESR1HPGDACHECA2
SCHEMBL21922672 0.87 ESR1 (0.44) ESR1HPGDACHELMNAMAPT
SCHEMBL18893005 0.86 ACHE (0.41) ESR1HPGDACHELMNAMAPT
SCHEMBL18893075 0.86 ACHE (0.41) ESR1HPGDACHELMNAMAPT
SCHEMBL20967392 0.86 LMNA (0.44) ESR1ACHELMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3643720-B1 ORGANIC COMPOUNDS, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC ELECTRONIC DEVICE NOVALED GMBH (DE) 2021-09-29 EP disclosed
EP-3643720-A1 ORGANIC COMPOUNDS, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2020-04-29 EP disclosed