Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 8/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15307251 | 0.81 | LPL (0.39) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL15587367 | 0.76 | MAP4K4 (0.39) | LPLLIPG | |
| SCHEMBL9948194 | 0.75 | LPL (0.57) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL21239904 | 0.74 | LPL (0.42) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL21630389 | 0.72 | CA1 (0.41) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL4160805 | 0.71 | CA1 (0.46) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL16655918 | 0.71 | LPL (0.41) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL31716916 | 0.71 | LIPG (0.46) | LPLLIPGCXCR2 | |
| SCHEMBL14748338 | 0.69 | LPL (0.50) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL17331609 | 0.69 | CA1 (0.43) | LPLLIPGCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855459-B1 | AMINOQUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-04-29 | — | — | EP | disclosed |